This impact corresponds to the project objectives (Strengthening excellence of SU in the field of EE, capacity building of SU in the field of Next Generation Sequencing Technologies). EE is a large group of epilepsy syndromes. Besides well defined classical electro-clinical syndromes, there is non-specific electro-clinical syndromes with complex phenotype. With the use of new genetic tools, genetic etiologies become more frequent than acquired causes. In the cohort of MMG (AMU) and NeuGen (SU), 20% and 34% of cases respectively have non phenotyped electro-clinical syndromes. A precise description of clinical symptoms, interpretation of EEG and the use of new genetic tools (e.g. NGS), need a high level of knowledge and technical capacity.
Through theoretical and practical training of the medical doctor, scientists, researchers and health professionals (e-learning, courses, workshops, seminars, fellowships for short stays, short term secondments), SEED project will allow SU to improve the skills and technical capacity of their members and then improve their results:
- In clinical and EEG diagnosis (WP3, 6): to improve the delay of clinical (from 4 to 2 months), rate of EEG diagnosis (from 75 to 100%) and then decrease the rate of non-phenotyped patients (from 34% to 25%).
- In the genetic diagnosis (WP4, 6): to improve the delay (from 1 year to 6 months) and the rate (from 15 to 25%) of genetic diagnosis.